Molecular chaperones are proteins that assist in the folding and unfolding of other proteins to help them achieve their proper three-dimensional structure. They play a crucial role in maintaining cellular homeostasis by preventing protein misfolding and aggregation, as well as aiding in the degradation of misfolded proteins. Molecular chaperones are involved in a wide range of cellular processes, such as protein synthesis, translocation, and degradation. They are also essential for the proper functioning of cells under stress conditions, such as heat shock or oxidative stress. Research in this area focuses on understanding the mechanisms by which molecular chaperones function, their roles in disease, and potential therapeutic strategies targeting chaperones to treat protein folding disorders.